Fitness costs associated with unnecessary virulence factors and life history traits: evolutionary insights from the potato late blight pathogen Phytophthora infestans.
Identifieur interne : 001915 ( Main/Exploration ); précédent : 001914; suivant : 001916Fitness costs associated with unnecessary virulence factors and life history traits: evolutionary insights from the potato late blight pathogen Phytophthora infestans.
Auteurs : Josselin Montarry [France] ; Frédéric M. Hamelin ; Isabelle Glais ; Roselyneère Corbi ; Didier AndrivonSource :
- BMC evolutionary biology [ 1471-2148 ] ; 2010.
Descripteurs français
- KwdFr :
- MESH :
- génétique : Phytophthora infestans, Virulence.
- microbiologie : Maladies des plantes, Solanum tuberosum.
- métabolisme : Phytophthora infestans.
- physiologie : Facteurs de virulence.
- Génotype, Évolution biologique.
English descriptors
- KwdEn :
- MESH :
- chemical , physiology : Virulence Factors.
- genetics : Phytophthora infestans, Virulence.
- metabolism : Phytophthora infestans.
- microbiology : Plant Diseases, Solanum tuberosum.
- Biological Evolution, Genotype.
Abstract
BACKGROUND
In gene-for-gene models of plant-pathogen interactions, the existence of fitness costs associated with unnecessary virulence factors still represents an issue, both in evolutionary biology and agricultural sciences. Measuring such costs experimentally has proven difficult, especially in pathogens not readily amenable to genetic transformation, since the creation of isogenic lines differing only by the presence or absence of avirulence genes cannot be achieved in many organisms. Here, we circumvented this difficulty by comparing fitness traits in groups of Phytophthora infestans isolates sharing the same multilocus fingerprint, but differing by their virulence/avirulence spectrum.
RESULTS
Fitness was assessed from calculations derived from the basic reproduction number, combining several life history traits (latent period, spore density and lesion growth rate) evaluated on leaflets of the potato cultivar Bintje, which is free of resistance genes. A statistically significant fitness cost was found in isolates virulent to the R10 resistance gene. That cost was due to a lower spore production in virulent isolates; however, the latent period was shorter in virulent isolates. Similar trends, although not statistically significant, were observed for the other genes tested.
CONCLUSION
The data likely reflect the adaptive response of the pathogen to the cost associated with virulence. They suggest strong trade-offs between life history traits related to pathogenicity and adaptive biology of pathogens.
DOI: 10.1186/1471-2148-10-283
PubMed: 20846405
PubMed Central: PMC2949872
Affiliations:
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Hamelin</name></author><author><name sortKey="Glais, Isabelle" sort="Glais, Isabelle" uniqKey="Glais I" first="Isabelle" last="Glais">Isabelle Glais</name></author><author><name sortKey="Corbi, Roselyneere" sort="Corbi, Roselyneere" uniqKey="Corbi R" first="Roselyneère" last="Corbi">Roselyneère Corbi</name></author><author><name sortKey="Andrivon, Didier" sort="Andrivon, Didier" uniqKey="Andrivon D" first="Didier" last="Andrivon">Didier Andrivon</name></author></titleStmt><publicationStmt><idno type="wicri:source">PubMed</idno><date when="2010">2010</date><idno type="RBID">pubmed:20846405</idno><idno type="pmid">20846405</idno><idno type="doi">10.1186/1471-2148-10-283</idno><idno type="pmc">PMC2949872</idno><idno type="wicri:Area/Main/Corpus">001837</idno><idno type="wicri:explorRef" wicri:stream="Main" wicri:step="Corpus" wicri:corpus="PubMed">001837</idno><idno type="wicri:Area/Main/Curation">001837</idno><idno type="wicri:explorRef" wicri:stream="Main" wicri:step="Curation">001837</idno><idno type="wicri:Area/Main/Exploration">001837</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en">Fitness costs associated with unnecessary virulence factors and life history traits: evolutionary insights from the potato late blight pathogen Phytophthora infestans.</title><author><name sortKey="Montarry, Josselin" sort="Montarry, Josselin" uniqKey="Montarry J" first="Josselin" last="Montarry">Josselin Montarry</name><affiliation wicri:level="3"><nlm:affiliation>INRA, Agrocampus-Ouest, UMR1099 BiO3P, Biology of Organisms and Populations applied to Plant Protection, F-35653 Le Rheu, France. josselin.montarry@avignon.inra.fr</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>INRA, Agrocampus-Ouest, UMR1099 BiO3P, Biology of Organisms and Populations applied to Plant Protection, F-35653 Le Rheu</wicri:regionArea><placeName><region type="region" nuts="2">Région Bretagne</region><settlement type="city">Le Rheu</settlement></placeName></affiliation></author><author><name sortKey="Hamelin, Frederic M" sort="Hamelin, Frederic M" uniqKey="Hamelin F" first="Frédéric M" last="Hamelin">Frédéric M. Hamelin</name></author><author><name sortKey="Glais, Isabelle" sort="Glais, Isabelle" uniqKey="Glais I" first="Isabelle" last="Glais">Isabelle Glais</name></author><author><name sortKey="Corbi, Roselyneere" sort="Corbi, Roselyneere" uniqKey="Corbi R" first="Roselyneère" last="Corbi">Roselyneère Corbi</name></author><author><name sortKey="Andrivon, Didier" sort="Andrivon, Didier" uniqKey="Andrivon D" first="Didier" last="Andrivon">Didier Andrivon</name></author></analytic><series><title level="j">BMC evolutionary biology</title><idno type="eISSN">1471-2148</idno><imprint><date when="2010" type="published">2010</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Biological Evolution (MeSH)</term><term>Genotype (MeSH)</term><term>Phytophthora infestans (genetics)</term><term>Phytophthora infestans (metabolism)</term><term>Plant Diseases (microbiology)</term><term>Solanum tuberosum (microbiology)</term><term>Virulence (genetics)</term><term>Virulence Factors (physiology)</term></keywords><keywords scheme="KwdFr" xml:lang="fr"><term>Facteurs de virulence (physiologie)</term><term>Génotype (MeSH)</term><term>Maladies des plantes (microbiologie)</term><term>Phytophthora infestans (génétique)</term><term>Phytophthora infestans (métabolisme)</term><term>Solanum tuberosum (microbiologie)</term><term>Virulence (génétique)</term><term>Évolution biologique (MeSH)</term></keywords><keywords scheme="MESH" type="chemical" qualifier="physiology" xml:lang="en"><term>Virulence Factors</term></keywords><keywords scheme="MESH" qualifier="genetics" xml:lang="en"><term>Phytophthora infestans</term><term>Virulence</term></keywords><keywords scheme="MESH" qualifier="génétique" xml:lang="fr"><term>Phytophthora infestans</term><term>Virulence</term></keywords><keywords scheme="MESH" qualifier="metabolism" xml:lang="en"><term>Phytophthora infestans</term></keywords><keywords scheme="MESH" qualifier="microbiologie" xml:lang="fr"><term>Maladies des plantes</term><term>Solanum tuberosum</term></keywords><keywords scheme="MESH" qualifier="microbiology" xml:lang="en"><term>Plant Diseases</term><term>Solanum tuberosum</term></keywords><keywords scheme="MESH" qualifier="métabolisme" xml:lang="fr"><term>Phytophthora infestans</term></keywords><keywords scheme="MESH" qualifier="physiologie" xml:lang="fr"><term>Facteurs de virulence</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Biological Evolution</term><term>Genotype</term></keywords><keywords scheme="MESH" xml:lang="fr"><term>Génotype</term><term>Évolution biologique</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en"><p><b>BACKGROUND</b></p><p>In gene-for-gene models of plant-pathogen interactions, the existence of fitness costs associated with unnecessary virulence factors still represents an issue, both in evolutionary biology and agricultural sciences. Measuring such costs experimentally has proven difficult, especially in pathogens not readily amenable to genetic transformation, since the creation of isogenic lines differing only by the presence or absence of avirulence genes cannot be achieved in many organisms. Here, we circumvented this difficulty by comparing fitness traits in groups of Phytophthora infestans isolates sharing the same multilocus fingerprint, but differing by their virulence/avirulence spectrum.</p></div><div type="abstract" xml:lang="en"><p><b>RESULTS</b></p><p>Fitness was assessed from calculations derived from the basic reproduction number, combining several life history traits (latent period, spore density and lesion growth rate) evaluated on leaflets of the potato cultivar Bintje, which is free of resistance genes. A statistically significant fitness cost was found in isolates virulent to the R10 resistance gene. That cost was due to a lower spore production in virulent isolates; however, the latent period was shorter in virulent isolates. Similar trends, although not statistically significant, were observed for the other genes tested.</p></div><div type="abstract" xml:lang="en"><p><b>CONCLUSION</b></p><p>The data likely reflect the adaptive response of the pathogen to the cost associated with virulence. They suggest strong trade-offs between life history traits related to pathogenicity and adaptive biology of pathogens.</p></div></front></TEI><pubmed><MedlineCitation Status="MEDLINE" Owner="NLM"><PMID Version="1">20846405</PMID><DateCompleted><Year>2010</Year><Month>12</Month><Day>22</Day></DateCompleted><DateRevised><Year>2018</Year><Month>11</Month><Day>13</Day></DateRevised><Article PubModel="Electronic"><Journal><ISSN IssnType="Electronic">1471-2148</ISSN><JournalIssue CitedMedium="Internet"><Volume>10</Volume><PubDate><Year>2010</Year><Month>Sep</Month><Day>16</Day></PubDate></JournalIssue><Title>BMC evolutionary biology</Title><ISOAbbreviation>BMC Evol Biol</ISOAbbreviation></Journal><ArticleTitle>Fitness costs associated with unnecessary virulence factors and life history traits: evolutionary insights from the potato late blight pathogen Phytophthora infestans.</ArticleTitle><Pagination><MedlinePgn>283</MedlinePgn></Pagination><ELocationID EIdType="doi" ValidYN="Y">10.1186/1471-2148-10-283</ELocationID><Abstract><AbstractText Label="BACKGROUND" NlmCategory="BACKGROUND">In gene-for-gene models of plant-pathogen interactions, the existence of fitness costs associated with unnecessary virulence factors still represents an issue, both in evolutionary biology and agricultural sciences. Measuring such costs experimentally has proven difficult, especially in pathogens not readily amenable to genetic transformation, since the creation of isogenic lines differing only by the presence or absence of avirulence genes cannot be achieved in many organisms. Here, we circumvented this difficulty by comparing fitness traits in groups of Phytophthora infestans isolates sharing the same multilocus fingerprint, but differing by their virulence/avirulence spectrum.</AbstractText><AbstractText Label="RESULTS" NlmCategory="RESULTS">Fitness was assessed from calculations derived from the basic reproduction number, combining several life history traits (latent period, spore density and lesion growth rate) evaluated on leaflets of the potato cultivar Bintje, which is free of resistance genes. A statistically significant fitness cost was found in isolates virulent to the R10 resistance gene. That cost was due to a lower spore production in virulent isolates; however, the latent period was shorter in virulent isolates. Similar trends, although not statistically significant, were observed for the other genes tested.</AbstractText><AbstractText Label="CONCLUSION" NlmCategory="CONCLUSIONS">The data likely reflect the adaptive response of the pathogen to the cost associated with virulence. They suggest strong trade-offs between life history traits related to pathogenicity and adaptive biology of pathogens.</AbstractText></Abstract><AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Montarry</LastName><ForeName>Josselin</ForeName><Initials>J</Initials><AffiliationInfo><Affiliation>INRA, Agrocampus-Ouest, UMR1099 BiO3P, Biology of Organisms and Populations applied to Plant Protection, F-35653 Le Rheu, France. josselin.montarry@avignon.inra.fr</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Hamelin</LastName><ForeName>Frédéric M</ForeName><Initials>FM</Initials></Author><Author ValidYN="Y"><LastName>Glais</LastName><ForeName>Isabelle</ForeName><Initials>I</Initials></Author><Author ValidYN="Y"><LastName>Corbi</LastName><ForeName>Roselyneère</ForeName><Initials>R</Initials></Author><Author ValidYN="Y"><LastName>Andrivon</LastName><ForeName>Didier</ForeName><Initials>D</Initials></Author></AuthorList><Language>eng</Language><GrantList CompleteYN="Y"><Grant><Agency>Biotechnology and Biological Sciences Research Council</Agency><Country>United Kingdom</Country></Grant></GrantList><PublicationTypeList><PublicationType UI="D016428">Journal Article</PublicationType><PublicationType UI="D013485">Research Support, Non-U.S. Gov't</PublicationType></PublicationTypeList><ArticleDate DateType="Electronic"><Year>2010</Year><Month>09</Month><Day>16</Day></ArticleDate></Article><MedlineJournalInfo><Country>England</Country><MedlineTA>BMC Evol Biol</MedlineTA><NlmUniqueID>100966975</NlmUniqueID><ISSNLinking>1471-2148</ISSNLinking></MedlineJournalInfo><ChemicalList><Chemical><RegistryNumber>0</RegistryNumber><NameOfSubstance UI="D037521">Virulence Factors</NameOfSubstance></Chemical></ChemicalList><CitationSubset>IM</CitationSubset><MeshHeadingList><MeshHeading><DescriptorName UI="D005075" MajorTopicYN="N">Biological Evolution</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D005838" 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D" first="Didier" last="Andrivon">Didier Andrivon</name><name sortKey="Corbi, Roselyneere" sort="Corbi, Roselyneere" uniqKey="Corbi R" first="Roselyneère" last="Corbi">Roselyneère Corbi</name><name sortKey="Glais, Isabelle" sort="Glais, Isabelle" uniqKey="Glais I" first="Isabelle" last="Glais">Isabelle Glais</name><name sortKey="Hamelin, Frederic M" sort="Hamelin, Frederic M" uniqKey="Hamelin F" first="Frédéric M" last="Hamelin">Frédéric M. Hamelin</name></noCountry><country name="France"><region name="Région Bretagne"><name sortKey="Montarry, Josselin" sort="Montarry, Josselin" uniqKey="Montarry J" first="Josselin" last="Montarry">Josselin Montarry</name></region></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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